Rifampicin-Induced Fever

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Rifampicin - Induced Fever

Rifampicin is a commonly used first-line antitubercular drug well known for its safety and efficacy and is generally well tolerated. Flu-like syndrome is the main cause of fever in rifampicin treated patients. High grade fever without accompanying features of hypersensitivity or flu is an extremely rare occurance. Our patient presented with pyrexia of unknown origin and diagnostic work-up revea...

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Rifampicin induced thrombocytopenia.

Rifampicin occasionally causes thrombocytopenia when given as part of an intermittent regimen. A case is reported of severe thrombocytopenia developing after one dose of rifampicin, following a 4-month gap in daily therapy. The literature on rifampicin-induced thrombocytopenia is reviewed.

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Pneumonitis induced by rifampicin.

An 81-year-old man was admitted to hospital with pulmonary Mycobacterium tuberculosis infection and was treated with rifampicin (RFP), isoniazid (INH), and ethambutol (EB). On day 9 he developed fever and dyspnoea. Chest radiographs showed new infiltration shadows in the right lung. Bronchoalveolar lavage (BAL) was performed and increased numbers of lymphocytes were recovered. Drug induced pneu...

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Rifampicin induced thrombocytopenia.

Thrombocytopenia is an uncommon but potentially life threatening complication of certain anti-tubercular drugs and is characterized by rapid destruction of platelets whenever an offending drug is taken by a susceptible person. Here is a case report of Rifampicin induced Thrombocytopenia. This case is being reported for purpose of its rare occurrence and documentation.

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Rifampicin-Induced Fever in a Patient with Brucellosis: A Case Report

We present a 35-year-old female patient who was started on rifampicin (900 mg orally once daily) and trimethoprim/sulfamethoxazole (TMP/SMX) (160/800 mg orally twice daily) after being diagnosed with brucellosis. Following defervescence and improvement in her general condition, fever recurred on the 12th day of treatment. A re-challenge drug test lead to causality assessment and treatment was s...

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ژورنال

عنوان ژورنال: IOSR Journal of Pharmacy and Biological Sciences

سال: 2012

ISSN: 2319-7676,2278-3008

DOI: 10.9790/3008-0212526